Progressive multiple cranial nerve palsies as the presenting symptom of meningeal carcinomatosis from occult colon adenocarcinoma.

Isolated acute hearing loss as the presenting symptom of leptomeningeal carcinomatosis.

Leptomeningeal carcinomatosis is characterized by diffuse infiltration of the meninges by metastatic cancer. We report a rare case of leptomeningeal carcinomatosis with an initial presentation of isolated acute hearing loss. Progressive unsteady gait and multiple cranial nerve palsies ensued. Computed tomography of the chest with contrast revealed a 2 cm nodule over the right upper lung. Cytolo...

Deafness and blindness as a presentation of colorectal meningeal carcinomatosis.

Multiple cranial nerve palsies often reveal a meningeal process that may be infectious, inflammatory, or neoplastic in origin. Even when there is a known history of malignancy, the rarity with which a given primary cancer causes meningeal carcinomatosis can influence diagnostic decision making and lead to delays in diagnosis. We present a unique case of a patient with deafness and blindness sec...

Meningeal carcinomatosis - an unusual cause of multiple cranial nerve palsies and sensory neuropathy.

Meningeal carcinomatosis and blindness.

The clinical syndrome of meningeal carcinomatosis includes headache, dementia, radiculopathy, and cranial nerve palsies. Blindness may be the first, or most prominent, symptom. When blindness occurs in adult life, meningeal carcinomatosis should be included in the differential diagnosis, even in the absence of other symptoms and in the absence of known malignancy. Although all pathophysiologica...

Metastatic Adenocarcinoma of Temporal Bone with Collet-Sicard Syndrome

Introduction: Metastatic tumors of the temporal bone are extremely rare. Collet-Sicard syndrome is an uncommon condition characterized by unilateral palsy of the lower four cranial nerves. The clinical features of temporal bone metastasis are nonspecific and mimic infections such as chronic otitis media and mastoiditis.   Case Report: This report describes a rare case of metastatic adenocarcino...